Ozempic and nutrient loss: a warning for those seeking rapid weight loss

"The prestigious scientific journal Frontiers in Nutrition (May 2025) published that users of GLP-1 medications such as Ozempic present significant deficiencies in essential nutrients, which could compromise their overall health if not accompanied by an appropriate nutritional strategy."

Publication date: May 30, 2025

The Ozempic phenomenon for weight loss , and its impact on health

Ozempic, the brand name for semaglutide , has become one of the most popular GLP-1 medications in Spain for treating obesity and type 2 diabetes. Its ability to promote rapid weight loss has garnered it significant attention, but recent research from GNC raises a major concern: users may be missing out on essential nutrients for their long-term well-being.

What does science say?

The study analyzed the eating habits of 69 adults who had been using GLP-1 (including Ozempic) for at least one month. The results showed a 20% reduction in total calorie intake, accompanied by a concerning deficiency in essential nutrients such as protein, calcium, magnesium, potassium, iron, vitamins A, C, D, E, and K, choline, and fiber.

These nutrients are essential for maintaining muscle mass, bone health, immune function, and metabolic balance. A deficiency can lead to problems such as muscle weakness, bone demineralization, anemia, fatigue, and digestive disorders.

Lack of information and follow-up

The study also revealed that only 51% of participants received information on how to manage the potential side effects of these medications, and a mere 20% were referred to a registered dietitian nutritionist to receive an appropriate dietary plan. This demonstrates the urgent need to include nutritional education as an essential part of treatment with Ozempic and other GLP-1 inhibitors .

Rachel Jones, senior vice president of innovation and science at GNC, emphasized: “The concern is not just how much weight is lost, but how it is lost. Muscle mass is essential, and we are seeing a widespread deficit in diet quality among GLP-1 users, which can have serious long-term consequences.”

What nutrients are key for Ozempic users?

For those taking Ozempic, it is essential to ensure that the following needs are met:

• High-quality proteins to maintain muscle mass and promote healthy weight loss.

• Calcium and magnesium , for bone health.

• Potassium , essential for muscle and nerve function.

• Iron , key to preventing anemia.

• Vitamins A, C, D, E and K , essential for immunity, cardiovascular health and metabolism.

• Choline and fiber , for digestive, liver and brain well-being.

The solution: education, nutrition, and personalized supplementation

In response to this reality, GNC has launched a comprehensive program to support GLP-1 users like Ozempic. This program focuses on addressing nutritional deficiencies and protecting gastrointestinal, muscular, and bone health through the use of targeted supplements. such as proteins, creatine, HMB, and vitamins and minerals tailored to each case.

In Spain, where Ozempic is increasingly popular, this strategy is gaining even more relevance. The key is to remember that losing weight shouldn't mean sacrificing your health. A balanced diet and the intelligent use of supplements can make all the difference.

A forward-looking approach to longevity

GLP-1 inhibitors , such as Ozempic, have revolutionized how we address obesity and diabetes, but their success shouldn't blind us to the risks of malnutrition. A combination of mindful nutrition, appropriate exercise, and professional guidance is essential for achieving healthy and sustainable weight loss.

"Time is no longer the enemy. It is an ally that we must nurture, cell by cell."