In 2025, the prestigious scientific journal Frontiers in Nutrition published a meta-analysis (PMID: 40308636) that reinforces turmeric's role as an ally for brain health. The study analyzed nine randomized clinical trials that included 501 participants with very diverse profiles: from adults with Alzheimer's, schizophrenia, or cognitive impairment following chemotherapy, to overweight people, women with PMS, and healthy older adults.
The results were clear: curcumin supplementation improved overall cognitive function compared to placebo.
Forms, doses and duration: the keys to benefit
Researchers evaluated multiple forms of curcumin. The doses studied ranged from 160 mg to 4 g daily, with durations ranging from 8 to 48 weeks.
Interestingly, the most effective dose identified was 800 mg daily for at least 24 weeks, especially when using formulations with greater bioavailability.
How does turmeric act on the brain?
The authors propose several mechanisms. On the one hand, they highlight its well-known antioxidant and anti-inflammatory effects, which are essential for protecting neurons from progressive damage. They also mention its ability to modulate amyloid activity and tau phosphorylation, processes implicated in neurodegenerative diseases such as Alzheimer's. Beyond the nervous system, they suggest that turmeric could influence cognition through the gut-brain axis and epigenetic mechanisms, opening up an interesting avenue for future exploration.
Conclusion: Real potential, but not all turmeric is created equal
This meta-analysis suggests that curcumin, especially at doses of 0.8 g/day for more than 24 weeks, may be a valuable tool for preserving cognitive function in older adults and people with certain risk factors. However, its efficacy will largely depend on the dosage form chosen: formulations with greater bioavailability appear to be crucial for achieving realistic results.
And this is where product selection becomes especially important. Longevitas' Cursol® Turmeric, thanks to its patented micellar structure and advanced stabilization technology, offers superior intestinal absorption compared to traditional forms. This makes it a particularly suitable option when seeking real, sustained cognitive effects.
“The mind is a fire that needs feeding, not a vessel to be filled.” Plutarch, Greek philosopher and biographer